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Braz. j. infect. dis ; 14(5): 513-518, Sept.-Oct. 2010. ilus
Article in English | LILACS | ID: lil-570569

ABSTRACT

This review will summarize the role of integrase in HIV-1 infection, the mechanism of integrase inhibitors and resistance with an emphasis on raltegravir (RAL), the first integrase inhibitor licensed to treat HIV-1 infection.


Subject(s)
Humans , Drug Resistance, Viral/genetics , HIV Infections/virology , HIV Integrase Inhibitors/pharmacology , HIV Integrase/genetics , HIV-1 , Virus Integration/drug effects , HIV Integrase/drug effects , HIV-1
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